|
rs1266078
|
BAG6;APOM
|
Blood Protein Measurement
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genomic atlas of the human plasma proteome.
|
29875488 |
2018 |
|
rs3117582
|
BAG6;APOM
|
Carcinoma of lung
|
|
0.760 |
GeneticVariation |
BEFREE |
As a result, 15 SNPs on or near 12 genes and one miRNA with strong evidence of association with lung cancer risk were identified, including TERT (rs2736098), CHRNA3 (rs1051730), AGPHD1 (rs8034191), CLPTM1L (rs401681 and rs402710), BAT3 (rs3117582), TRNAA (rs4324798), ERCC2 (Lys751Gln), miR-146a2 (rs2910164), CYP1B1 (Arg48Gly), GSTM1 (null/present), SOD2 (C47T), IL-10 (-592C/A and -819C/T), and TP53 (intron 6).
|
29110844 |
2017 |
|
rs3117582
|
BAG6;APOM
|
Malignant neoplasm of lung
|
|
0.760 |
GeneticVariation |
BEFREE |
As a result, 15 SNPs on or near 12 genes and one miRNA with strong evidence of association with lung cancer risk were identified, including TERT (rs2736098), CHRNA3 (rs1051730), AGPHD1 (rs8034191), CLPTM1L (rs401681 and rs402710), BAT3 (rs3117582), TRNAA (rs4324798), ERCC2 (Lys751Gln), miR-146a2 (rs2910164), CYP1B1 (Arg48Gly), GSTM1 (null/present), SOD2 (C47T), IL-10 (-592C/A and -819C/T), and TP53 (intron 6).
|
29110844 |
2017 |
|
rs3117582
|
BAG6;APOM
|
Primary malignant neoplasm of lung
|
|
0.060 |
GeneticVariation |
BEFREE |
As a result, 15 SNPs on or near 12 genes and one miRNA with strong evidence of association with lung cancer risk were identified, including TERT (rs2736098), CHRNA3 (rs1051730), AGPHD1 (rs8034191), CLPTM1L (rs401681 and rs402710), BAT3 (rs3117582), TRNAA (rs4324798), ERCC2 (Lys751Gln), miR-146a2 (rs2910164), CYP1B1 (Arg48Gly), GSTM1 (null/present), SOD2 (C47T), IL-10 (-592C/A and -819C/T), and TP53 (intron 6).
|
29110844 |
2017 |
|
rs139789464
|
BAG6;APOM
|
Carcinoma of lung
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
|
28604730 |
2017 |
|
rs139789464
|
BAG6;APOM
|
Squamous cell carcinoma of lung
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
|
28604730 |
2017 |
|
rs805297
|
BAG6;APOM
|
Thrombophilia
|
|
0.010 |
GeneticVariation |
BEFREE |
ApoM rs805297 polymorphism was significantly associated with higher risk of VTE recurrence in males but not in females on both univariate (p= 0.038, hazard ratio = 1.72, confidence interval = 1.03-2.88) and on multivariate analysis adjusted with mild and severe thrombophilia, family history, location and acquired risk factors for VTE.
|
27277397 |
2016 |
|
rs805297
|
BAG6;APOM
|
Venous Thromboembolism
|
|
0.010 |
GeneticVariation |
BEFREE |
ApoM rs805297 was significantly associated with higher risk of VTE recurrence in male but not in female patients.
|
27277397 |
2016 |
|
rs9404941
|
BAG6;APOM
|
Venous Thromboembolism
|
|
0.010 |
GeneticVariation |
BEFREE |
However, ApoM rs9404941 polymorphism showed no significant association with risk of VTE recurrence in all patients as well as in different gender groups.
|
27277397 |
2016 |
|
rs805296
|
BAG6;APOM
|
Coronary Artery Disease
|
|
0.020 |
GeneticVariation |
BEFREE |
ApoM rs805296 polymorphism may be a risk factor for developing CAD.
|
26723879 |
2016 |
|
rs805296
|
BAG6;APOM
|
Coronary Arteriosclerosis
|
|
0.010 |
GeneticVariation |
BEFREE |
Meta-Analysis on the Correlation Between APOM rs805296 Polymorphism and Risk of Coronary Artery Disease.
|
26723879 |
2016 |
|
rs805296
|
BAG6;APOM
|
Coronary heart disease
|
|
0.010 |
GeneticVariation |
BEFREE |
Meta-Analysis on the Correlation Between APOM rs805296 Polymorphism and Risk of Coronary Artery Disease.
|
26723879 |
2016 |
|
rs3117582
|
BAG6;APOM
|
Sarcoidosis
|
C |
0.700 |
GeneticVariation |
GWASCAT |
High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences.
|
26651848 |
2016 |
|
rs3117582
|
BAG6;APOM
|
Malignant neoplasm of lung
|
|
0.760 |
GeneticVariation |
BEFREE |
We found also that BAG6 rs3117582 SNP was associated with non small cell lung cancer in the Norwegian subjects and the combined Croatian-Norwegian subjects corroborating the earlier finding that BAG6 rs3117582 SNP was associated with lung cancer in Europeans.
|
25884493 |
2015 |
|
rs3117582
|
BAG6;APOM
|
Carcinoma of lung
|
|
0.760 |
GeneticVariation |
BEFREE |
We found also that BAG6 rs3117582 SNP was associated with non small cell lung cancer in the Norwegian subjects and the combined Croatian-Norwegian subjects corroborating the earlier finding that BAG6 rs3117582 SNP was associated with lung cancer in Europeans.
|
25884493 |
2015 |
|
rs3117582
|
BAG6;APOM
|
Primary malignant neoplasm of lung
|
|
0.060 |
GeneticVariation |
BEFREE |
We found also that BAG6 rs3117582 SNP was associated with non small cell lung cancer in the Norwegian subjects and the combined Croatian-Norwegian subjects corroborating the earlier finding that BAG6 rs3117582 SNP was associated with lung cancer in Europeans.
|
25884493 |
2015 |
|
rs3117582
|
BAG6;APOM
|
Non-Small Cell Lung Carcinoma
|
|
0.010 |
GeneticVariation |
BEFREE |
We found also that BAG6 rs3117582 SNP was associated with non small cell lung cancer in the Norwegian subjects and the combined Croatian-Norwegian subjects corroborating the earlier finding that BAG6 rs3117582 SNP was associated with lung cancer in Europeans.
|
25884493 |
2015 |
|
rs3117582
|
BAG6;APOM
|
Degenerative polyarthritis
|
|
0.010 |
GeneticVariation |
BEFREE |
Family with sequence similarity 46, member A (FAM46A) gene VNTR and BCL2-Associated Athanogene 6 (BAG6) gene rs3117582 polymorphisms were genotyped in a case-control study with 474 large-joint (hip and knee) osteoarthritis (OA) patients and 568 controls in Croatian population by candidate-gene approach for association with OA.
|
25231575 |
2015 |
|
rs3117582
|
BAG6;APOM
|
Osteoarthritis, Knee
|
|
0.010 |
GeneticVariation |
BEFREE |
We found that BAG6 rs3117582 SNP genotypes were associated with protection (major allele homozygote) and susceptibility (major-minor allele heterozygote) to OA.
|
25231575 |
2015 |
|
rs3117582
|
BAG6;APOM
|
Osteoarthritis of hip
|
|
0.010 |
GeneticVariation |
BEFREE |
Susceptibility to large-joint osteoarthritis (hip and knee) is associated with BAG6 rs3117582 SNP and the VNTR polymorphism in the second exon of the FAM46A gene on chromosome 6.
|
25231575 |
2015 |
|
rs3117582
|
BAG6;APOM
|
Malignant neoplasm of lung
|
|
0.760 |
GeneticVariation |
BEFREE |
Furthermore, BAT3 rs3117582 increased lung cancer risk (OR = 1.31, 95 % CI, 1.26-1.35, P < 0.00001).
|
24989925 |
2014 |
|
rs3117582
|
BAG6;APOM
|
Carcinoma of lung
|
|
0.760 |
GeneticVariation |
BEFREE |
Furthermore, BAT3 rs3117582 increased lung cancer risk (OR = 1.31, 95 % CI, 1.26-1.35, P < 0.00001).
|
24989925 |
2014 |
|
rs3117582
|
BAG6;APOM
|
Primary malignant neoplasm of lung
|
|
0.060 |
GeneticVariation |
BEFREE |
Furthermore, BAT3 rs3117582 increased lung cancer risk (OR = 1.31, 95 % CI, 1.26-1.35, P < 0.00001).
|
24989925 |
2014 |
|
rs3117582
|
BAG6;APOM
|
Lupus Erythematosus, Systemic
|
G |
0.700 |
GeneticVariation |
GWASDB |
GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.
|
24871463 |
2014 |
|
rs3117582
|
BAG6;APOM
|
Tuberculosis
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of variable number of tandem repeats in the coding region of the FAM46A gene, FAM46A rs11040 SNP and BAG6 rs3117582 SNP with susceptibility to tuberculosis.
|
24625963 |
2014 |